HANDONG KESAIJINONG HOLDINGS CO., LTD. Unveils Patented Herbicide Toxapyzone(P) – A Breakthrough in Green Weed Control and Resistance Management
In the broader narrative of safeguarding global food security, pesticides play an indispensable role as a critical means of production. However, for a long time, with the spread of herbicide-resistant weeds, the effectiveness of existing herbicides against a variety of difficult-to-control cropland weeds has been steadily declining. At the same time, safety concerns for subsequent crops and growing environmental issues have become increasingly acute, calling for a new technological revolution.
After years of dedicated technical research, SHANDONG KESAIJINONG HOLDINGS CO., LTD. has launched its latest R&D and application achievement – Toxapyzone(P) – a compound that has received high recognition from industry experts. This compound has achieved significant breakthroughs in green weed control, resistant weed management, and multi-crop adaptability, providing new momentum for the green development of global agriculture.

Toxapyzone(P)
· Chemical name: 1-((4-(3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoyl)-1-methyl-1H-pyrazol-5-yl)oxy)ethyl methyl carbonate
· InChi Key: RCDMJWFAYGGGTA-UHFFFAOYSA-N
· Molecular formula: C₂₀H₂₃N₃O₈S
· Molecular weight: 465.477
· Pesticide classification: Pyrazole compound

Key Features and Advantages
Toxapyzone(P) offers a range of outstanding characteristics: a well-defined target site, low environmental toxicity, low application dosage (achieving ideal results at 1.5–2 grams of active ingredient per mu under normal conditions), rapid efficacy, and strong crop safety. Its overall performance surpasses that of similar products such as topramezone and tembotrione.
Intellectual Property and Registration Status
SHANDONG KESAIJINONG HOLDINGS CO., LTD. filed a patent for this compound on November 3, 2023, and was granted an invention patent on May 24, 2024 (Patent No.: ZL 202311455118.9). On May 6, 2024, the company submitted a PCT patent application, obtaining International Patent Application No. PCT/CN2024/091133, with ongoing global patent portfolio expansion. The product has now officially initiated the registration process with the Chinese Ministry of Agriculture and Rural Affairs.
Field Performance and Application Scope
After two years of multi-location demonstration trials, the product has demonstrated outstanding efficacy against a wide range of weed species, including green foxtail (Setaria viridis), crabgrass (Digitaria spp.), barnyard grass (Echinochloa crus-galli), goosegrass (Eleusine indica), reed (Phragmites spp.), bermudagrass (Cynodon dactylon), redroot pigweed (Amaranthus retroflexus), common lambsquarters (Chenopodium album), purslane (Portulaca oleracea), velvetleaf (Abutilon theophrasti), and nutsedge (Cyperus rotundus). It provides excellent control of grasses, broadleaf weeds, and sedges alike. The compound also exhibits soil activity.

Recent studies have shown that Toxapyzone(P) is not only effective in corn fields but also demonstrates strong adaptability in wheat, sugarcane, and rice fields, as well as non-crop areas – significantly broadening its application potential. Its effectiveness in non-crop land weed management is particularly noteworthy, contributing to the control of resistant weeds in these areas.
Enhanced Formulation for Real-World Conditions
Through formulation and process optimization, SHANDONG KESAIJINONG HOLDINGS CO., LTD. has endowed the product with excellent rainfastness, ensuring stable efficacy even under adverse weather conditions. This makes it well-suited for the climatic demands of the rainy season in Nigeria and other tropical agricultural regions.
Commitment to Innovation and Sustainability
The innovative development of Toxapyzone(P) marks a significant step forward in advancing cropland weed control technologies toward greater efficiency and ecological sustainability. "Innovation, Reliability, and Long-termism" is the R&D philosophy of SHANDONG KESAIJINONG HOLDINGS CO., LTD.. The company will continue to increase investment in technology R&D, collaborate with research institutions, and develop more efficient, green, and low-risk agrochemical products and technologies. Through science and technology, the company is committed to supporting global food security and green, high-quality agricultural development, providing sustained momentum for increasing crop production and stabilizing yields worldwide – and safeguarding every inch of cultivated land with science and responsibility.
SHANDONG KESAIJINONG HOLDINGS CO., LTD. – Innovation for a Greener, More Secure Agricultural Future.

